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A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.

Substitution Animals Antiviral Agents Benzodioxoles Cattle Cell Line Diarrhea Virus 1, Bovine Viral Diarrhea Virus 2, Bovine Viral Drug Resistance, Viral Hepacivirus Inhibitory Concentration 50 Models, Molecular ...

Characterization of pathogenic and resistant genome repertoire reveals two clonal lines in Salmonella enterica subsp. enterica serovar Paratyphi B (+)-tartrate positive.

Dose-Response Relationship, Drug Drug Resistance, Bacterial Drug Resistance, Multiple, Bacterial Genetic Variation Germany Humans Microbial Sensitivity Tests Netherlands Oligonucleotide Array Sequence Analysis ...

Potential of antiviral therapy and prophylaxis for controlling RNA viral infections of livestock.

treatment and up to 12h post-infection. Such prophylactic/therapeutic antiviral drugs could complement emergency vaccination in a previously disease-free setting or be applied to treat valuable zoological ...

Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase.

Res, Volume 77, Issue 2, p.114-9 (2008) Keywords: Amino Acid Substitution Animals Antiviral Agents Cell Line Classical swine fever virus Diarrhea Viruses, Bovine Viral Drug Resistance, Viral Imaging, ...

An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells.

Issue 5, p.380-91 (2007) Keywords: Amiloride B-Lymphocytes Caco-2 Cells Cell Differentiation Coculture Techniques Drug Carriers Epithelial Cells Humans immunohistochemistry Intestinal Mucosa Microscopy, ...

2'-C-methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virus.

2’-C-MetCyt resulted in a (1.6-3.2)x10(3)-fold reduction of infectious virus yield. Time-of-drug addition experiments suggest that 2’-C-MetCyt interacts with viral replication at a time point that coincides ...

Delivery of DNA vaccines by agarose hydrogel implants facilitates genetic immunization in cattle.

Keywords: Animals Cattle Cattle Diseases Delayed-Action Preparations Diffusion Drug Implants Excipients Feces Herpesvirus 1, Bovine Hydrogels Immunization Immunization Schedule Inflammation Neutralization ...

Validation of a method for the detection and confirmation of nitroimidazoles and the corresponding hydroxymetabolites in pig plasma by LC-MS/MS

Publication Type: Scientific poster, presentation or proceeding Authors: Stéphanie Fraselle; Joris Van Loco; Derop,V.; J-M Degroodt Source: 5th International Symposium on Hormone and Veterinary Drug ...

A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.

Johan Source: J Virol, Volume 80, Issue 1, p.149-60 (2006) Keywords: Antiviral Agents Diarrhea Virus 1, Bovine Viral Drug Resistance, Viral Imidazoles Lethal Dose 50 Mutation Pestivirus Pyridines RNA ...

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