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Setting specifications for Biologicals. Points to consider from simple to complex. Case study for viral vectored vaccines.

Cambridge, MA, USA (2017) Keywords: vaccine Health Topics:  Vaccine batch conformity Vaccin lot conformiteit Conformité de lot de vaccin Service:  Qualité des vaccins et produits sanguins Kwaliteit van vaccins ...

Impact of caspase-1/11,-3,-7, or IL-1/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease.

been used as an oral vaccine for animals. Infection of Mf4/4 macrophages with both strains led to caspase-1 activation and IL-1 and IL-18 production, as well as activation of caspases-3,-7,-8, and-9. ...

Attenuation of RNA viruses by redirecting their evolution in sequence space.

in ‘risky’ areas of sequence space may be implemented as a broad-spectrum vaccine strategy against RNA  viruses. Health Topics:  Influenza Influenza Service:  Maladies virales Virale ziekten Viral ...

Characterization of two recombinant HVT-IBD vaccines by VP2 insert detection and cell-mediated immunity after vaccination of specific pathogen-free chickens.

Diseases Specific Pathogen-Free Organisms Vaccination Vaccines, Synthetic Viral Structural Proteins Viral Vaccines Abstract: Infectious bursal disease (IBD) is an avian viral disease that causes severe ...

Us3 and Us9 proteins contribute to the stromal invasion of bovine herpesvirus 1 in the respiratory mucosa.

and Us9 during BHV-1 infection in the respiratory mucosa. First, we constructed and characterized BHV-1 Us3 null, Us9 null and revertant viruses. Then, we analysed the viral replication and plaque size ...

Introduction of liquid-based cytology and human papillomavirus testing in cervical cancer screening in Luxembourg.

studies DNA, Viral Early Detection of Cancer Female Humans Luxembourg middle aged Neoplasm Grading Papillomaviridae Papillomavirus Infections Practice Guidelines as Topic Pregnancy prevalence Squamous ...

Three Different Routes of Inoculation for Experimental Infection with Schmallenberg Virus in Sheep.

Sheep Sheep Diseases Spleen Vaccination Abstract: Schmallenberg virus (SBV) is an emerging Orthobunyavirus affecting European domestic ruminants. In this study, three groups of ewes (n = 3) were ...

Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines.

Viral Base Sequence Bluetongue Bluetongue virus Capsid Proteins Cattle Cell Line Drug Stability Drug Storage Female Male Reverse Genetics Serogroup Sheep Vaccination Vaccines, Attenuated Vaccines, Subunit ...

Pre-registration efficacy study of a novel marker vaccine against classical swine fever on maternally derived antibody positive (MDA+) target animals.

(2017) Keywords: Animals Biomarkers Classical Swine Fever Female Male Maternal-Fetal Exchange Pregnancy Swine Viral Vaccines Abstract: Maternally Derived Antibodies (MDA) can have a negative effect on the ...

Epidemiology, Impact and Control of Rabies in Nepal: A Systematic Review

epidemiology Impact Nepal Rabies Abstract: Background Rabies is a vaccine-preventable viral zoonosis belonging to the group of neglected tropical diseases. Exposure to a rabid animal may result in a fatal acute ...

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