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Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...
The analysis of cannabinoids in e-cigarette liquids using LC-HRAM-MS and LC-UV.
using the ‘total error’ approach, applying accuracy profiles and conforming to ISO17025. None of the analysed samples exceeded the legal limit for the total amount of ∆9- THC present. However, of the 20 ...
The analysis of cannabinoids in e-cigarette liquids using LC-HRAM-MS and LC-UV
applying accuracy profiles and conforming to ISO17025. None of the analysed samples exceeded the legal limit for the total amount of ∆9- THC present. However, of the 20 CBD-liquids investigated in this ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells
microarray profiles of 24 (non-)genotoxic reference chemicals covering different modes of action in metabolically competent human HepaRG™ cells. In the present study, new prediction models for genotoxicity ...
CBD oils on the Belgian market: A validated MRM GC-MS/MS method for routine quality control using QuEChERS sample clean up
(0.05–0.1–0.2% (w/v)) for CBN. The detection limits for CBT, CBD, CBC, Δ8- THC, CBN and for the other cannabinoids of interest, were 10 and 14 ng/mL respectively. The accuracy profile values for CBD and CBN showed ...
Development of a real-time PCR method for the genoserotyping of Salmonella Paratyphi B variant Java.
Paratyphi B is of major importance as these two variants have different pathogenic profiles. While D-tartrate non-fermenting S. Paratyphi B isolates are the causative agent of typhoid-like fever, D-tartrate ...
A simple dilute-and-shoot method for screening and simultaneous quantification of nicotine and alkaloid impurities in electronic cigarette refills (e-liquids) by UHPLC-DAD
Biomedical Analysis, Volume 169, Issue 169, Number 234 (2019) Keywords: accuracy profiles e-cigarettes Nicotine nicotine-impurities UHPLC-DAD Abstract: The electronic cigarette (e-cigarette) has emerged as ...
Analysis of illegal peptide drugs via HILIC-DAD-MS.
(MS) and quantification via UV. Validation was performed via accuracy profiles based on the ISO 17025 guideline. The obtained validated HILIC-method allows for the detection and quantification of the ...
Development and validation of a HS/GC-MS method for the simultaneous analysis of diacetyl and acetylpropionyl in electronic cigarette refills
5ppm for diacetyl and acetylpropionyl. The obtained accuracy profiles show that the beta-expectation tolerance intervals did not exceed the acceptance limits of+/-10%, meaning that 95% of future ...
Accuracy profiles assessing the validity for routine use of high-performance thin-layer chromatographic assays for drug formulations
validity Abstract: The accuracy profile, based on total error, integrates several validation parameters, such as trueness, precision and linearity, providing one statistic which enables decision on the ...