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Characterisation of tetanus monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.

Antoine Francotte; Paul Stickings Source: Biologicals, Volume 71 (2021) Keywords: Animal Testing Alternatives Animals Antibodies, Monoclonal Immunoassay Tetanus Tetanus Toxoid Vaccine Potency Abstract: ...

Characterisation of diphtheria monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.

having been specifically developed as alternatives to in vivo potency tests. These methods require at least one well characterised monoclonal antibody (mAb) that is specific for the target antigen. In this ...

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