Search results - 6 results
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
phenotypic Drug Susceptibility Testing (DST) of M. tuberculosis (Mtb), multiple DNA-based methods were successfully introduced over the last years. Although these are fast and sensitive, they (a) are based on ...
Simultaneous determination of anti-tuberculosis drug levels in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry for subsequent Therapeutic Drug Monitoring
Toxicology and Therapeutic Drug Monitoring- IATDMCT Satellite Meeting 2014, NA, Issue IATDMCT, NA (2014) Keywords: alternative Anti tubercolosis drugs DRUG Drug Monitoring Human LC-MS/MS LEVEL levels Liquid ...
Synthesis and biological evaluation of benzo[j]phenanthrideine-7,12-diones as anti-tuberculosis agents
Publication Type: Scientific poster, presentation or proceeding Authors: J. Jacobs Source: 2nd International Conference on pharmaceutics and novel drug delivery systems, Pharmaceutica Analytica ...
The anti-cancer drug 5-fluorouracil is highly active against Mycobacterium tuberculosis in vitro but not in vivo
Pathogenesis and Control of Emerging Infections and Drug-Resistant Organisms, NA, Issue Keystone Symposia, NA (2008) Keywords: Control DRUG in vivo INFECTION infections IS Mycobacterium Mycobacterium ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
of resistance. Materials & Methods First, the global transcriptional response of two TB strains to 10 anti- TB drugs was determined using RNA taq-Seq. A set of highly responsive genes was selected for each ...
Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid
counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains to ...