Search results - 10 results
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
phenotypic Drug Susceptibility Testing (DST) of M. tuberculosis (Mtb), multiple DNA-based methods were successfully introduced over the last years. Although these are fast and sensitive, they (a) are based on ...
Synthesis and anti-tubercular activity of N(2)-arylbenzo[g]isoquinoline-5,10-dione-3-iminium bromides.
tuberculosis and the susceptibility of a multi-drug-resistant strain towards the compound was confirmed. Health Topics: Health and disease monitoring Category: A1 FOS Classification: 3.03 Health sciences ...
Simultaneous determination of anti-tuberculosis drug levels in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry for subsequent Therapeutic Drug Monitoring
Toxicology and Therapeutic Drug Monitoring- IATDMCT Satellite Meeting 2014, NA, Issue IATDMCT, NA (2014) Keywords: alternative Anti tubercolosis drugs DRUG Drug Monitoring Human LC-MS/MS LEVEL levels Liquid ...
Anti-mycobacterial activity of 1,3-diaryltriazenes.
spread of the drug resistant tuberculosis has led to an ongoing demand for novel compounds for therapeutic use. Identification and study of compounds with the ability to inhibit Mycobacterium tuberculosis ...
Biological evaluation of diazene derivatives as anti-tubercular compounds.
generation and spread of drug resistant strains, a problem exacerbated by co-infection with HIV demands further efforts in the investigation of novel classes of anti-tubercular compounds. A library of eight ...
Biological evaluation of bisbenzaldehydes against four Mycobacterium species.
microwave-assisted reactions, were evaluated in vitro against drug susceptible and multi-drug resistant Mycobacterium tuberculosis, against virulent Mycobacterium bovis, against Mycobacterium ulcerans and against two ...
An update on vaccines for tuberculosis- there is more to it than just waning of BCG efficacy with time.
Trials, Phase I as Topic Clinical Trials, Phase II as Topic Humans Tuberculosis Tuberculosis Vaccines Abstract: INTRODUCTION: Apart from better diagnostics and new anti-microbial drugs, an effective vaccine ...
Synthesis and biological evaluation of benzo[j]phenanthrideine-7,12-diones as anti-tuberculosis agents
Publication Type: Scientific poster, presentation or proceeding Authors: J. Jacobs Source: 2nd International Conference on pharmaceutics and novel drug delivery systems, Pharmaceutica Analytica ...
The anti-cancer drug 5-fluorouracil is highly active against Mycobacterium tuberculosis in vitro but not in vivo
Pathogenesis and Control of Emerging Infections and Drug-Resistant Organisms, NA, Issue Keystone Symposia, NA (2008) Keywords: Control DRUG in vivo INFECTION infections IS Mycobacterium Mycobacterium ...
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid.
incidence and counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains ...