Search results - 4 results
The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.
resistance, or consistent with susceptibility, for 13 WHO endorsed anti-tuberculosis drugs. 38,215 MTBC isolates with paired whole-genome sequencing and phenotypic drug susceptibility testing data were amassed ...
Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.
at least rifampicin, isoniazid, any fluoroquinolone and one of the injectable anti-tuberculosis drugs, remains a worldwide public health threat. Among repurposed drugs empirically used for XDR- TB ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
of resistance. Materials & Methods First, the global transcriptional response of two TB strains to 10 anti- TB drugs was determined using RNA taq-Seq. A set of highly responsive genes was selected for each ...
Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid
counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains to ...