Search results - 21 results
Biological evaluation of diazene derivatives as anti-tubercular compounds.
generation and spread of drug resistant strains, a problem exacerbated by co-infection with HIV demands further efforts in the investigation of novel classes of anti-tubercular compounds. A library of eight ...
Biological evaluation of bisbenzaldehydes against four Mycobacterium species.
microwave-assisted reactions, were evaluated in vitro against drug susceptible and multi-drug resistant Mycobacterium tuberculosis, against virulent Mycobacterium bovis, against Mycobacterium ulcerans and against two ...
An update on vaccines for tuberculosis- there is more to it than just waning of BCG efficacy with time.
Trials, Phase I as Topic Clinical Trials, Phase II as Topic Humans Tuberculosis Tuberculosis Vaccines Abstract: INTRODUCTION: Apart from better diagnostics and new anti-microbial drugs, an effective vaccine ...
Synthesis and biological evaluation of benzo[j]phenanthrideine-7,12-diones as anti-tuberculosis agents
Publication Type: Scientific poster, presentation or proceeding Authors: J. Jacobs Source: 2nd International Conference on pharmaceutics and novel drug delivery systems, Pharmaceutica Analytica ...
Straightforward palladium-mediated synthesis and biological evaluation of benzo[j]phenanthridine-7,12-diones as anti-tuberculosis agents
development of novel anti-tuberculosis drugs. Benzo[j]phenanthridine-7,12-diones, tetracyclic derivatives of the natural product benz[g]isoquinoline-5,10-dione, were conveniently synthesized via ...
The effect of combined tobramycin-clarithromycin on Mycobacterium tuberculosis isolates36841
Keywords: 0 a administration & dosage Agent Agents Anti-Bacterial Agents article AS Belgium Brussels Clarithromycin Clinical delivery DRUG Drug Delivery Systems drug effects Drug Resistance,Microbial Drug ...
The anti-cancer drug 5-fluorouracil is highly active against Mycobacterium tuberculosis in vitro but not in vivo
Pathogenesis and Control of Emerging Infections and Drug-Resistant Organisms, NA, Issue Keystone Symposia, NA (2008) Keywords: Control DRUG in vivo INFECTION infections IS Mycobacterium Mycobacterium ...
Antimycobacterial activity of synthetic pamamycins
Source: J.Antimicrob.Chemother., Volume 54, Issue 4, Number 827, p.824- 827 (2004) Keywords: 0 Activity Agent Agents Anti-Bacterial Agents Antifungal Agents Antimicrobial article AS bacteria Belgium ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
of resistance. Materials & Methods First, the global transcriptional response of two TB strains to 10 anti- TB drugs was determined using RNA taq-Seq. A set of highly responsive genes was selected for each ...
Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid
counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains to ...