Search results - 8 results

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

and Benjamini-Hochberg corrected p-values. Mutations were graded as Associated with Resistance if present in at least 5 isolates, if the odds ratio was >1 with a statistically significant corrected ...

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

improved identification of non-tuberculous mycobacterial species, and iv) an updated statistical model for Oxford Nanopore Technologies sequencing data. is released under MIT license at ...

Strong increase of true and false positive mycobacterial cultures sent to the National Reference Centre in Belgium, 2007 to 2016.

observational study investigated the numbers of analyses at the NRC and false positive cultures (interpreted as containing mycobacteria at referring clinical laboratories, but with no mycobacterial DNA detected ...

Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study.

assays in tuberculosis (TB) laboratory diagnosis requires effective management of time and resources. OBJECTIVE: To further develop and assess at multiple centres a time-and-motion (T&M) tool as an ...

Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.

at least rifampicin, isoniazid, any fluoroquinolone and one of the injectable anti-tuberculosis drugs, remains a worldwide public health threat. Among repurposed drugs empirically used for XDR- TB ...

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

of the mammalian cell entry family, that were identical with Mah 104 strain. Despite the obvious limitations of the mouse model, a striking link of virulence and identity at the genome level of porcine ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

tuberculosis complex were correctly classified (5⅖2), while 126 of the 142 Non-tuberculosis Mycobacteria were accurately identified at a 1.65 cut-off. Recently, it was described that MALDI- TOF MS can also be ...

WIV-ISP's experiences in the use of MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Mycobacteria and their drug resistance profiles. By using an optimized extraction protocol, they successfully identified 88.14 % of 194 Mycobacterial strains at a species-level and 3.09 % at genus-level, using ...

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