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Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid

found with components that affect aerobic respiration. This demonstrates that, besides the inhibition of cell wall synthesis, respiratory poisoning plays a fundamental role in the bactericidal effect of ...

Falsification of biotechnology drugs: current dangers and/or future disasters?

Publication Type: Peer reviewed scientific article Authors: Steven Janvier; De Spiegeleer, Bart; Celine Vanhee; Eric Deconinck Source: J Pharm Biomed Anal, Volume 161 (2018) Keywords: Biological ...

Comparison of SNP-based subtyping workflows for bacterial isolates using WGS data, applied to Salmonella enterica serotype Typhimurium and serotype 1,4,[5],12:i:.

PLoS One, Volume 13, Issue 2 (2018) Keywords: bacterial phylogeny; food-borne; genes; NGS; WGS; computational biology/bioinformatics; disease outbreaks; outbreak; performance evaluation; pipeline; ...

Monitoring of Laboratory-Acquired Infections

the inherent safe nature of GMO s (“biological containment”), whether or not in combination with adherence to effective safety measures. Most of the reported LAI s are infections with wild-type, ...

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans

comparative interactomics of multiple strains is an effective strategy to highlight correlations between host proteome hijacking and biological or pathogenic traits. Here, we developed an interactomic pipeline ...

Invasion by the Alien Tree Alters Ecosystem Functions in a Temperate Deciduous Forest

biogeochemical cycles biological invasion canopy foliar nutrients exotic species heterotrophic respiration invasive species litter Abstract: Alien invasive species can affect large areas, often with wide-ranging ...

Toxicology of silica nanoparticles: an update

Toxicity of SiNPs in vitro is size, dose, and cell type dependent. SiNPs synthesized by wet route exhibited noticeably different biological effects compared to thermal route-based SiNPs. Amorphous SiNPs ...

Dermal exposure of Belgian florists to insecticide residues

Issue KU Leuven, NA (2017) Keywords: an AS at Belgium biological sciences chromatography Combination effect exposure florist GC Hand health Lead LEVEL levels measure method national ON Order pesticide ...

An application of mass spectrometry for quality control of biologicals: Highly sensitive profiling of plasma residuals in human plasma-derived immunoglobulin.

information required. BIOLOGICAL SIGNIFICANCE: This study characterized residual plasma proteins in Ig products, using bottom-up LC- MS / MS with conventional data-dependent acquisition, preceded by sample fractionation. ...

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