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M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.

virus-like particles presenting M2 e (M2 e- VLP s). We produced the VLP s with and without entrapped nucleic acids and compared their immunogenicity and protective efficacy. Immunization of BALB /c mice with ...

Seroprevalence and potential risk factors for Brucella spp. infection in traditional cattle, sheep and goats reared in urban, periurban and rural areas of Niger.

cattle, the odds of brucellosis seropositivity were higher in rural compared to the periurban areas (OR of 2.8; 95% CI: 1.48-5.17) whereas for small ruminants the risk of seropositivity appeared to be ...

A proteomics approach for the quantification of Staphylococcus aureus enterotoxins a and b in several matrices using uplc-msms analysis.

validating this method according to ISO 2002/657/ EC. When comparing the MS spectra peaks found for the IS and the endogenous peptides we were able to identify and quantify the presence of SEA and/or SEB in ...

Routinely-collected general practice data from the electronic patient record and general practitioner active electronic questioning method: A comparative study

Clinical Comparative Study Comparison Computerized patient record conditions data Data collection de diabete diabetes DRUG drugs electronic ET general General practice GENERAL PRACTITIONER general ...

End-of-life decisions: a cross-national study of treatment preference discussions and surrogate decision-maker appointments

of patient participation in end-of-life decision-making. This study estimates and compares the prevalence of GP-patient end-of-life treatment discussions and patients’ appointment of surrogate ...

Clinical value of IS6110-based loop-mediated isothermal amplification for detection of Mycobacterium tuberculosis complex in respiratory specimens

study (2008-2009), IS6110- LAMP was evaluated on 101 sputum specimens from 93 highly suspected TB patients and compared to Amplicor MTB test and in-house IS6110- PCR and-nested PCR assays. Culture results ...

Nationwide continuous monitoring of end-of-life care via representative networks of general practitioners in Europe

BACKGROUND: Although end-of-life care has become an issue of great clinical and public health concern in Europe and beyond, we lack population-based nationwide data that monitor and compare the circumstances of ...

End-of-life medical treatment preference discussions and surrogate decision-maker appointments: evidence from Italy, Spain, Belgium and the Netherlands

anticipation of possible future incapacity is an important part of patient participation in end-of-life decision-making. AIM: To compare the prevalence of GP-patient end-of-life treatment discussions and patient ...

Prevalence and viral load of 51 genital human papillomavirus types and three subtypes

but declined to HSIL. From NIL /M to HSIL, Hr- HPV infections showed an increasing frequency of high viral loads compared to total DNA positivity, but the increase between LSIL and HSIL was small. ...

High-risk HPV testing on self-sampled versus clinician-collected specimens: A review on the clinical accuracy and impact on population attendance in cervical cancer screening

Cervical Intraepithelial Neoplasia CERVICAL-CANCER Clinical Combination comparing Countries cytology Database detection developed countries electronic HPV Human identify im Impact improve IS IT journal ...

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