Search results - 14 results
Microbial quality analysis of falsified medicines seized by controling agencies
could potentially be pathogenic upon oral uptake of the samples. Our results indicate that 50% of the samples were not compliant for their microbial quality (see Table 7), indicating that improper ...
Multidimensional chromatographic fingerprinting combined with chemometrics for the identification of regulated plants in suspicious plant food supplements
multiclass models could be made. Furthermore, it can be concluded that the combination of chemometrics and multi-wavelength chromatographic fingerprinting is a promising approach for identifying plants using ...
COMBINATION OF CHEMOMETRICS AND MULTIDIMENSIONAL FINGERPRINTING FOR DETECTION OF REGULATED PLANTS IN PLANT FOOD SUPPLEMENTS
Even though both models showed good correct classification rates (%), the multiclass model could give problems when two or more of the targeted plants are present, since it is only able to classify with ...
Clustering of Tadalafil API Samples According to their Manufacturer in the Context of API Falsification Detection
spectrometric screening, X-ray powder diffraction and proton nuclear magnetic resonance (1 H- NMR). Chemometric analysis revealed that all manufacturers could be characterised based on the impurity, residual ...
Multidimensional Fingerprint Development for the Detection of Tribulus terrestris in Plant Food Supplements
triturations, Tribulus could visually be detected from concentration 1/10 onwards, by comparing the fingerprints with the reference plant. A market study of a total of 20 samples (with potency enhancement as ...
Relative response factors and multiple regression models in liquid chromatography to quantify low-dosed components using alternative standards-proof of concept: total Δ9-THC content in cannabis flowers using CBD as reference.
have limited shelf-life properties. Also, in herbal matrices, multiple compounds could be necessary to be quantified, needing a whole series of different (related) reference standards. In these cases, ...
Detection of regulated and prohibited plants in plant food supplements
presence of chemical adulterants like sibutramine and analogues in slimming preparations or sildenafil and analogues in potency enhancers. Other underestimated problems with these herbal preparations could ...
Use of near infrared spectroscopy and chemometrics for the classification of different Cannabis spp. samples found in Belgium
prove that NIR spectroscopy could be used as a preliminary screening method for the authorities to make the decision to seize or not. Health Topics: Médicaments illégaux Illegal medicines Illegale ...
GEONs API fingerprint project: Selection of analytical techniques for clustering of sildenafil citrate API samples
chromatography for residual solvents, X-ray diffraction and Nuclear Magnetic Resonance (NMR) spectroscopy. Chemometrics applied to the collected data showed that all manufacturers could be discriminated based on ...
European fingerprint study on omeprazole drug substances using a multi analytical approach and chemometrics as a tool for the discrimination of manufacturing sources
Pharmacopoeia, and collecting analytical fingerprints that could be further used to differentiate manufacturing sources for future authenticity investigations. The study described in this article reports the ...