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genotoxicity

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Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo

exposed to these suspensions for 24 h and endpoints such as cytotoxicity, total glutathione, epithelial barrier integrity, inflammatory mediators and DNA damage were measured. Large agglomerates of 17 nm ...

In Vitro and In Vivo Toxicity Studies on Cymbopogon giganteus Chiov. Leaves Essential Oil from Benin

administration of a single dose of 5% or 2% v/v. Single doses of 0.125% or 0.5% v/v did not induce inflammation, cell recruitment nor cytotoxicity in lungs 3 h or 24 h after administration, suggesting safety at ...

Is aggregated synthetic amorphous silica toxicologically relevant?

far, it is indeed believed that large aggregates represent a weaker hazard compared to their nano counterpart. Thus, we assessed the impact of SAS aggregation on in vitro cytotoxicity/biological activity ...

Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

not clear. We assessed the toxicological response to HNT s (NaturalNano (NN)) before and after surface etching (NN-etched). Potential cytotoxicity of the two HNT s was screened in vitro in MutaTMMouse ...

In vitro toxicity, genotoxicity and antigenotoxicity of Nigella sativa extracts from different geographic locations

Number 141 (2019) Keywords: antigenotoxicity cytotoxicity genotoxicity Geographic location Nigella sativa Seed extracts Abstract: Nigella sativa or black cumin is used as a spice and as a natural remedy ...

Phytochemical analysis, antioxidant, anticoagulant and in vitro toxicity and genotoxicity testing of methanolic and juice extracts of Beta vulgaris L.

genotoxicity or cytotoxic effects. The results show the potential of the plant, especially the juice, as a new source of bioactive molecules for therapeutic purposes, possibly in the treatment of ...

Antimutagenicity, antioxidant activity and cytotoxicity of n-tetracosanol, eiocosanoic acid and arjunolic acid isolated from Combretum microphyllum (Combretaceae)

(2017) Keywords: acid Activity ALL an Antimutagenicity Antioxidant activity Arjunolic acid AS at cancer chronic Combretum microphyllum cytotoxicity Development disease Diseases effect effects Eicosanoic ...

Impact of caspase-1/11,-3,-7, or IL-1/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease.

Death Discov, Volume 3, p.17012 (2017) Abstract: Rabies virus is a highly neurovirulent RNA virus, which causes about 59000 deaths in humans each year. Previously, we described macrophage cytotoxicity ...

Genotoxicity and genomic instability caused by intermediate frequency magnetic fields in rat astrocytes

Comet Assay cytotoxicity Genomic Instability genotoxicity intermediate frequencies Micronucleus test Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation ...

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