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Biosafety of Gene Therapy Vectors Derived From Herpes Simplex Virus Type 14581

the other hand, other HSV-1 derived vectors which also have a promising perspective in the clinic, are designed to have enhanced cytotoxicity in certain cell types, as in the case of oncolytic vectors. ...

Biological evaluation of bisbenzaldehydes against four Mycobacterium species.

an intracellular growth inhibition assay of M. tb in murine J774 A.1 macrophages. None of the compounds showed significant cytotoxicity on human C3A hepatocytes in a neutral red dye uptake assay and no ...

Investigation into the genotoxicity of water extracts from Hypoxis species and a commercially available Hypoxis preparation.

assay in human hepatoma HepG2 cells. The relative cytotoxicity of these samples was established by determining their NI50 values (50% inhibition of NRU), and these results were used for dose-finding in ...

Permeability of gloves to selected chemotherapeutic agents after treatment with alcohol or isopropyl alcohol.

protection for health care professionals frequently exposed to cytotoxic agents are reported. METHODS: The permeation of 17 cytotoxic drugs through different glove materials and glove combinations was studied ...

1,4-diarylpiperazines and analogs as anti-tubercular agents: synthesis and biological evaluation36446

Volume 49, Number 101, p.95- 101 (2012) Keywords: 1 4-Diarylpiperazines Anti-mycobacterial activity cytotoxicity Mycobacterium tuberculosis Abstract: Despite progress in modern chemotherapy to combat ...

Genotoxicity of water extracts from hypoxis species

cytotoxicity of these samples was established by determining their NI50 values (50% inhibition of NRU), and these results were used for dose-finding in genotoxicity tests. None of the tested extracts were ...

Antibacterial, antifungal and cytotoxic activities of two flavonoids from Retama raetam flowers

Keywords: Retama raetam flowers; antibacterial activity; antifungal activity; cytotoxic property; flavonoid Abstract: We investigated the antibacterial, antifungal and cytotoxic activities of two new ...

Mutagenicity, antimutagenicity and cytotoxicity evaluation of South African Podocarpus species

Keywords: Antimutagenicity cytotoxicity mutagenicity Podocarpus Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Four species of Podocarpus are used in traditional medicine both in human and animal healthcare in ...

Straightforward palladium-mediated synthesis and biological evaluation of benzo[j]phenanthridine-7,12-diones as anti-tuberculosis agents

drug molecules against M. tuberculosis and on their cytotoxicity on C3A human hepatocytes. The strongest antimicrobial activity (as detected by growth inhibition of bacteria, using luminometry and BACTEC ...

Evaluation of cytotoxicity and genotoxicity of some Philippine medicinal plants

Number 175 (2011) Keywords: cytotoxicity genotoxicity medicinal plants Plant Extracts Pogostemon cablin Ricinus communis Health Topics:  Health and environment Santé et environnement Gezondheid en milieu ...

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