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Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.
epoxide-bearing analogs ATX- II, ATX- III, and STTX- III show the highest cytotoxic, genotoxic, and mutagenic potential in vitro. Under hormone-sensitive conditions, AOH and AME act as moderate xenoestrogens, but ...
Identifying nanodescriptors to predict the toxicity of nanomaterials: a case study on titanium dioxide
modelling. Agglomerate size as a nanodescriptor was well associated with biological endpoints such as DNA damage and/or cytotoxicity. We conclude that, agglomerate size is an important nanodescriptor to assess ...
Investigation into the genotoxicity of water extracts from Hypoxis species and a commercially available Hypoxis preparation.
assay in human hepatoma HepG2 cells. The relative cytotoxicity of these samples was established by determining their NI50 values (50% inhibition of NRU), and these results were used for dose-finding in ...
Functional characterization of in vivo effector CD4(+) and CD8(+) T cell responses in acute Toxoplasmosis: an interplay of IFN-gamma and cytolytic T cells.
Issue 13, p.2556-64 (2010) Keywords: Animals Antigens, Protozoan CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes Cytotoxicity, Immunologic Female Interferon-gamma Macrophages Membrane Proteins mice ...