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genotoxicity

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In Vitro and In Vivo Toxicity Studies on Cymbopogon giganteus Chiov. Leaves Essential Oil from Benin

a single dose of 5% or 2% v/v. Single doses of 0.125% or 0.5% v/v did not induce inflammation, cell recruitment nor cytotoxicity in lungs 3 h or 24 h after administration, suggesting safety at these ...

Anti-mycobacterial activity of 1,3-diaryltriazenes.

as Mycobacterium bovis, Mycobacterium avium and Mycobacterium ulcerans. Although the library of the compounds showed a considerable acute cytotoxicity, a genotoxicity could not be observed. Finally, ...

Biological evaluation of bisbenzaldehydes against four Mycobacterium species.

an intracellular growth inhibition assay of M. tb in murine J774 A.1 macrophages. None of the compounds showed significant cytotoxicity on human C3A hepatocytes in a neutral red dye uptake assay and no ...

Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.

mice Mice, Inbred C57BL Mice, Knockout T-Lymphocytes, Cytotoxic Tuberculosis Vaccines Vaccination Vaccines, DNA Abstract: Reactivation tuberculosis (TB) is a serious problem in immunocompromised ...

Induction of in vivo functional Db-restricted cytolytic T cell activity against a putative phosphate transport receptor of Mycobacterium tuberculosis.

Histocompatibility Antigen H-2D Interferon-gamma Interleukin-2 mice Mice, Inbred C57BL Molecular Sequence Data Mycobacterium tuberculosis T-Lymphocytes, Cytotoxic Th1 Cells Tuberculosis Vaccines Vaccines, DNA ...

Culture filtrate specific H-2(b) restricted CD8+ T cells activated in vivo by Mycobacterium tuberculosis or bovis BCG recognize a restricted number of immunodominant peptides.

(2002) Keywords: Animals Antigens, Bacterial ATP Binding Cassette Transporter, Subfamily B, Member 3 ATP-Binding Cassette Transporters CD8-Positive T-Lymphocytes Culture Media, Conditioned Cytotoxicity ...

What are the immunologically active components of bacille Calmette-Guérin in therapy of superficial bladder cancer?

We purified various BCG subcomponents and analyzed in vitro their ability to enhance a Th1 polarized immune response as well as to increase lymphocyte-mediated cytotoxicity against bladder tumors. ...

Characterization of the culture filtrate-specific cytotoxic T lymphocyte response induced by Bacillus Calmette-Guérin vaccination in H-2b mice.

CD8-Positive T-Lymphocytes Cell Line Chloroquine Culture Media H-2 Antigens Interferon-gamma Lymphocyte Activation Membrane Glycoproteins mice Mice, Inbred C57BL Perforin Pore Forming Cytotoxic Proteins ...

Characterization of the culture filtrate-specific cytotoxic T lymphocyte response induced by bacillus Calmette-Guérin vaccination in H-2b mice

bacille Calmette-Guérin BFA Brefeldin A CF culture filtrate CTL cytotoxic T lymphocytes culture filtrate antigens cytotoxic T lymphocytes Mycobacterium bovis bacillus Calmette-Guérin TAP ...

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