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Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
DNA microarray profiles of 24 (non-)genotoxic reference chemicals covering different modes of action in metabolically competent human HepaRG™ cells. In the present study, new prediction models for ...
Occurrence of microcystin congeners in surface waters and food in Belgium as a source of exposure to humans
environmental samples. This has a negative downstream effect on possible risk assessment studies that would establish the exposure and influence of the different cyanotoxins on public health, and on the final ...
Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety
two different STEC strains, and we could cluster separately the reads corresponding to each strain and perform relatedness (phylogeny), however not all genes harbored in the isolate’s genome could be ...
Comparison of 6 DNA extraction methods for isolation of high yield of high molecular weight DNA suitable for shotgun metagenomics Nanopore sequencing to detect bacteriaAbstractBackgroundResultsConclusion
level, were specifically designed for this application and need to be assessed. Results: In this study, with different bacterial cocktail mixes, analyzed as pure or spiked in a synthetic fecal matrix, we ...
Evaluation of the types, efficient use and health risks of application of silver-based biocides to provide antimicrobial properties to face masks applied during the Covid-19 crisis
biocides in face masks using electron microscopy and EDX, combined with total silver measurement using ICP- MS or ICP- OES demonstrated the presence of varying amounts and different types of silver-based ...
In Silico Methods for Chromosome Damage.
prediction tools for chromosome damage is applied on a dataset of pharmaceuticals. Examples of the different outcomes obtained with the in silico battery are provided and briefly discussed. Furthermore, ...
A Summer of Cyanobacterial Blooms in Belgian Waterbodies: Microcystin Quantification and Molecular Characterizations
different protocols and is restricted to some selected recreational ponds and lakes. Therefore, a global assessment based on the comparison of existing datasets is not possible. For this study, 79 water ...
Variability in the association between long-term exposure to ambient air pollution and mortality by exposure assessment method and covariate adjustment: A census-based country-wide cohort study
with age as the underlying time scale and adjusted for various individual and area-level covariates. We further adjusted main models for two different area-levels following the European Nomenclature of ...
Air pollution in association with mental and self-rated health and the mediating effect of physical activity
40.1% (NO2-poor self-rated health) of the association may be mediated by a difference in physical activity. Conclusions Long-term exposure to PM2.5, BC or NO2 was adversely associated with multiple ...
Higher buccal mtDNA content is associated with residential surrounding green in a panel study of primary school children
high (≥3m) and total (sum of low and high) green space within different radii (100m–1000m) from the residence and distance to the nearest large green space (>0.5ha) were estimated using a remote ...