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Detection of toxins involved in foodborne diseases caused by Gram‐positive bacteria

mode of action and dose‐response profile. This review focuses on biological, immunological, mass spectrometry, and molecular assays as the most commonly used detection and quantification methods for ...

ADVANCE database characterisation and fit for purpose assessment for multi-country studies on the coverage, benefits and risks of pertussis vaccinations.

population (size, representatively of age/sex of national population, rounding of birth dates, delay between birth and database entry), vaccinations (number of vaccine doses, recording of doses, pattern of ...

Risk assessment of aflatoxins in food

exposure. Aflatoxins are genotoxic and AFB1 can cause hepatocellular carcinomas (HCC s) in humans. The CONTAM Panel selected a benchmark dose lower confidence limit (BMDL) for a benchmark response of 10% of ...

Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

epithelial cells. Lung inflammation, acute phase response and genotoxicity were assessed 1, 3, and 28 days after a single intratracheal instillation of adult female C57BL /6 J BomTac mice. The doses were 6, 18 ...

Food groups and risk of coronary heart disease, stroke and heart failure: A systematic review and dose-response meta-analysis of prospective studies

disease Diet dose-response food Heart Failure meta-analysis Stroke Abstract: Background: Despite growing evidence for food-based dietary patterns’ potential to reduce cardiovascular disease risk, knowledge ...

Time of administration of rabies immunoglobulins and adequacy of antibody response upon post-exposure prophylaxis: a descriptive retrospective study in Belgium.

Belgium are scarce. The main objective of this study was to evaluate the timely administration of HRIG after rabies exposure. The secondary objective was to evaluate the adequate antibody response following ...

Genotoxic evaluation of the liquids present in electronic cigarettes

immunological responses in animal models. Whether these findings are also relevant to humans remains unclear. [Aim]   The genotoxic potential of flavouring substances present in e-cigarettes was studied using ...

Migration of mineral oil from cardboard packaging for food: Identification of the hazards and assessment of the exposure of the Belgian population

carcinogenic, no adequate dose-response carcinogenicity data are available and consequently, no MOE-based risk assessment could be performed.  Two worst‐case scenarios were applied to obtain some preliminary ...

Global burden of intellectual disability resulting from dietary exposure to lead, 2015

an uncertainty range of 0-31 million DALY s. Significant uncertainties regarding exposure and dose-response relationships, however, warrant continued investigation. Health Topics:  Burden of disease ...

Generating the evidence for risk reduction: a contribution to the future of food-based dietary guidelines.

categorical comparisons, but also on linear and non-linear dose-response associations. Risk of bias of the individual studies of the meta-analysis should be assessed, rated and the overall credibility of the ...

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