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Towards clinical breakpoints for non-tuberculous mycobacteria- Determination of epidemiological cut off values for the Mycobacterium avium complex and Mycobacterium abscessus using broth microdilution.
their importance for establishing antimicrobial susceptibility testing (AST) breakpoints. METHODS: We gathered MIC distributions for drugs used against the Mycobacterium avium complex (MAC) and ...
In vitro antigenotoxic activity, in silico ADME prediction and protective effects against aflatoxin B1 induced hepatotoxicity in rats of an Erythrina latissima stem bark extract
aglycones (11.82%) and glycosides (16.17%). ADME, pharmacokinetic and drug-likeness assessment of major flavonoids of ELBE, using the web tool SwissADME, showed good oral bioavailability. The protective ...
Isoniazid Bactericidal Activity Involves Electron Transport Chain Perturbation.
inhibition. The activity of isoniazid (INH), a key first-line bactericidal antituberculosis drug currently known to inhibit mycolic acid synthesis, becomes extremely poor under stress conditions, such as ...
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid
incidence and counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
Issue 9, p.2215-29 (2016) Keywords: Carcinogens Cell Line, Tumor Computational Biology Dose-Response Relationship, Drug Gene Expression Profiling Gene Expression Regulation Genome-Wide Association Study ...
In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics.
Source: Skin Pharmacol Physiol, Volume 29, Issue 6, p.300-308 (2016) Keywords: Adult Drug and Narcotic Control Female Humans Hydroquinones In Vitro Techniques Male middle aged Reproducibility of Results ...
Increased B and T Cell Responses in M. bovis Bacille Calmette-Guerin Vaccinated Pigs Co-Immunized with Plasmid DNA Encoding a Prototype Tuberculosis Antigen
vaccines DRUG electronic health im immunology INFECTION Institute intradermal IS journal lymphocyte M MODEL Netherlands ON Pig Pigs protection protein public public health Public-health Ratio region Research ...
Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Drug Resistance, Viral Enzyme Inhibitors Hepacivirus Models, Molecular Mutation Protein Conformation Pyridines RNA Replicase Virus Replication Abstract: 2,6-Bis(benzimidazol-2-yl)pyridine (BBP / CSFA-0) ...
4-Methyl-amphetamine: a health threat for recreational amphetamine users.
Volume 27, Issue 9, p.817-22 (2013) Keywords: Amphetamine Amphetamine-Related Disorders Amphetamines Dopamine Agents Drug users Humans Methamphetamine Netherlands Serotonin Agents Substance Abuse Detection ...
Antimicrobial resistance in the food chain: a review34030
Drug Resistance,Bacterial electronic food Food Chain Food Handling Food Microbiology gene Genes health Human Humans im Increase IS journal microorganism microorganisms ON pathogen pathogenic POLICIES ...