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Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Drug Resistance, Viral Enzyme Inhibitors Hepacivirus Models, Molecular Mutation Protein Conformation Pyridines RNA Replicase Virus Replication Abstract: 2,6-Bis(benzimidazol-2-yl)pyridine (BBP / CSFA-0) ...
Towards licensing of CP7_E2alf as marker vaccine against classical swine fever-Duration of immunity.
(2012) Keywords: Administration, Oral Animals Antibodies, Viral Classical Swine Fever Drug Approval Injections, Intramuscular Survival Analysis Swine Vaccines, Marker Viral Vaccines Abstract: Classical ...
A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.
Substitution Animals Antiviral Agents Benzodioxoles Cattle Cell Line Diarrhea Virus 1, Bovine Viral Diarrhea Virus 2, Bovine Viral Drug Resistance, Viral Hepacivirus Inhibitory Concentration 50 Models, Molecular ...
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
replication. The 50% effective concentration values for inhibition of bovine viral diarrhea virus (BVDV)-induced cytopathic effect, viral RNA synthesis, and production of infectious virus were 1.2 +/- 0.5 ...
2'-C-methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virus.
(FMDV). FMDV belongs to the Picornaviridae and has the potential to cause devastating epidemics in livestock. The 50% and 90% effective concentrations (EC50 and EC90) for inhibition of the FMDV-induced ...
Social context affects testosterone-induced singing and the volume of song control nuclei in male canaries (Serinus canaria).
Animals brain Canaries Dominance-Subordination Drug Implants Female Male Orchiectomy Sexual Behavior, Animal Social Behavior Testosterone Vocalization, Animal Abstract: The contribution of social factors to ...
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Johan Source: J Virol, Volume 80, Issue 1, p.149-60 (2006) Keywords: Antiviral Agents Diarrhea Virus 1, Bovine Viral Drug Resistance, Viral Imidazoles Lethal Dose 50 Mutation Pestivirus Pyridines RNA ...
Attenuation of bovine leukemia virus by deletion of R3 and G4 open reading frames.
BLV; p30, p13, and p12 for HTLV). As a virus/animal model for HTLV-induced leukemogenesis, BLV provirus can be injected intradermally into sheep, where it induced B-lymphocyte transformation. Deletion of ...
Immunity and effect of clopidol/methyl benzoquate and robenidine before and after weaning on rabbit coccidiosis in the field.
E perforans significantly, whereas clopidol/methyl benzoquate reduced oocyst output of the latter four species only and was least active against E magna. Both drugs also reduced coccidiosis-induced mortality ...
Dietary silver nanoparticles can disturb the gut microbiota in mice.
Mihaly; Marbaix, Etienne; Lison, Dominique Source: Part Fibre Toxicol, Volume 13, Issue 1, p.38 (2016) Keywords: Animals Dose-Response Relationship, Drug Intestines Metal Nanoparticles mice Microbiota ...