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A Benchmark Dose-based strategy for evaluating the combined effects of genotoxic compounds

Belgium (2023) Keywords: benchmark dose modelling genotoxicity mixtures Health Topics:  Food consumption and food safety Consommation et sécurité alimentaires Voedselconsumptie en –veiligheid Service:  ...

Towards Characterization and genotoxicity assessment of mycotoxin mixtures present in food.

Mertens Source: BelTox Annual Meeting, Brussels, Belgium (2023) Keywords: additivity benchmark dose modelling genotoxicity mixtures Mycotoxins Health Topics:  Food consumption and food safety Consommation ...

The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)

Source: Joint 3R Symposium 2023 (2023) Keywords: genotoxicity NAMs transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des ...

An AOP-based IATA to pave the way toward animal-free genotoxicity testing

Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: adverse outcome pathways genotoxicity ...

Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals

Source: 57th Congress of the European Societies of Toxicology (Eurotox 2023), Ljubljana, Slovenia (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health ...

Mixtures of genotoxicants: does the principle of additivity apply?

Belgium (2023) Keywords: additivity benchmark dose modelling genotoxicity mixtures Mycotoxins Health Topics:  Food consumption and food safety Consommation et sécurité alimentaires Voedselconsumptie en ...

Mixtures of genotoxicants: does the principle of additivity apply?

Keywords: additivity benchmark dose modelling genotoxicity mixtures Mycotoxins Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des risques et de ...

The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells

Source: EEMGS meeting, Malaga, Spain (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid ...

Development of an AOP-based IATA for genotoxicity

O Armant; C Pachoulide; H Bouwmeester; G Raitano; E Benfenati; E Wyrzykowska; M Stepnik; T Puzyn; M Audebert; Birgit Mertens Source: EEMGS meeting (2023) Keywords: adverse outcome pathways genotoxicity ...

The GENOMARK biomarker inhuman HepaRGTM cells: a new approach methodology for genotoxicity assessment

SaferWorldByDesign webinar, Online (2023) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des risques et de ...

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