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Position paper on the use of an “estimated acceptable concentration” (EAC) as basis for a control policy's action level for carcinogens unintentionally present in food
Vleminckx; Van Huffel, Xavier; Peter Hoet Source: Trends in Food Science & Technology (2020) Keywords: Carcinogen Food safety management genotoxic ‘Margin of exposure’ (MOE) Abstract: Background In the ...
New QSAR models to predict chromosome damaging potential based on the in vivo micronucleus test
Emilio Source: Toxicology Letters, Volume 329, Number 84 (2020) Keywords: Chromosome damage genotoxicity In silico model In vivo micronucleus QSAR Abstract: A large number of computer-based prediction ...
Risk assessment of ochratoxin A in food
tumours in rodents. OTA is genotoxic both in vitro and in vivo; however, the mechanisms of genotoxicity are unclear. Direct and indirect genotoxic and non‐genotoxic modes of action might each contribute to ...
Comments on the “Evaluation of the Genotoxicity of Cell Phone Radiofrequency Radiation in Male and Female Rats and Mice Following Subchronic Exposure” by Smith‐Roe et al.
Number 295 (2020) Keywords: brain Comet Assay DNA Damage glioma Micronucleus assay Sprague Dawley Abstract: Comment on Evaluation of the genotoxicity of cell phone radiofrequency radiation in male and ...
Risk assessment of aflatoxins in food
exposure. Aflatoxins are genotoxic and AFB1 can cause hepatocellular carcinomas (HCC s) in humans. The CONTAM Panel selected a benchmark dose lower confidence limit (BMDL) for a benchmark response of 10% of ...
Anti-mycobacterial activity of 1,3-diaryltriazenes.
as Mycobacterium bovis, Mycobacterium avium and Mycobacterium ulcerans. Although the library of the compounds showed a considerable acute cytotoxicity, a genotoxicity could not be observed. Finally, ...
Biological evaluation of diazene derivatives as anti-tubercular compounds.
three compounds showed signs of genotoxicity by VITOTOX or by Comet assay. The study was complemented by demonstration of the inhibition of intracellular replication of M.tb H37R v inside J774 A.1 cells ...
Biological evaluation of bisbenzaldehydes against four Mycobacterium species.
genotoxicity or mutagenicity was observed as demonstrated by a VITOTOX ™ test and confirmed with a comet assay. Health Topics: Health and disease monitoring Category: A1 FOS Classification: 3.03 Health ...