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Biological evaluation of diazene derivatives as anti-tubercular compounds.

three compounds showed signs of genotoxicity by VITOTOX or by Comet assay. The study was complemented by demonstration of the inhibition of intracellular replication of M.tb H37R v inside J774 A.1 cells ...

Genotoxicity evaluation of nanosized titanium dioxide, synthetic amorphous silica and multi-walled carbon nanotubes in human lymphocytes.

properties of NM s, including size and morphology, might influence their toxicity and have impact on human health. The present work aimed to evaluate the genotoxicity of nanosized titanium dioxide (TiO2), ...

Synthesis and antimycobacterial activity of analogues of the bioactive natural products sampangine and cleistopholine36497

against a multi-drug-resistant MDR LAM-1 M.tb strain was tested and the MIC value situated around 1 muM. The lacking genotoxicity of a group of enamine substituted cleistopholine analogues indicates this ...

Investigation on the genotoxicity of extracts from Cleome amblyocarpa Barr. and Murb, an important Tunisian medicinal plant

(2013) Keywords: Cleoma amblyocarpa Comet Assay diabetes genotoxicity methanol extract neutral red uptake test toxicity Abstract: We conducted an investigation of the Manuscript versions:  DOI:  ...

Scientific opinion on the risk for public and animal health related to the presence of sterigmatocystin in food and feed

method methods mycotoxins,sterigmatocystin,food,feed,dietary exposure,genotoxic and carcinogenic,risk assessment need observed occurrence ON Pig Pigs Poultry public Quantification result results risk ...

Biological evaluation of bisbenzaldehydes against four Mycobacterium species.

genotoxicity or mutagenicity was observed as demonstrated by a VITOTOX ™ test and confirmed with a comet assay. Health Topics:  Health and disease monitoring Category:  A1 FOS Classification:  3.03 Health ...

High-throughput bacterial mutagenicity testing:VITOTOX assay.

Hoboken, NJ, USA, p.570 (2013) ISBN: 978-1-118-06563-1 Keywords: Ames test genotoxicity high throughput sceening toxicity Vitotox Manuscript versions:  DOI:  http://dx.doi.org/10.1002/9781118538203.ch11 ...

Investigation into the genotoxicity of water extracts from Hypoxis species and a commercially available Hypoxis preparation.

p.350-6 (2013) Keywords: Comet Assay DNA Damage Humans Hypoxis Mutagenicity Tests Mutagens Plant Extracts Abstract: We performed an in vitro evaluation of the genotoxic potential of water extracts from four ...

Scientific opinion on emerging and novel brominated flame retardants (BFRs) in food

bioaccumulation potential. There is convincing evidence that tris(2,3-dibromopropyl) phosphate (TDBPP) and dibromoneopentyl glycol (DBNPG) are genotoxic and carcinogenic, warranting further surveillance of their ...

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