Search results - 328 results

Identifying nanodescriptors to predict the toxicity of nanomaterials: a case study on titanium dioxide

the development of alternative testing strategies such as computational (predictive) models based on in vitro testing. However, the variations in in vitro experimental conditions can influence the ...

Identification of flavouring substances of genotoxic concern present in e-cigarette refills

transhexanal, there was a clear concern for in vivo genotoxicity. A selection of 4 out of the remaining 22 flavourings was tested in two in vitro genotoxicity assays. Three out of the four tested flavourings ...

Characterisation of diphtheria monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.

paper we report the results of the comprehensive characterisation of a panel of mAbs against diphtheria with a view to select antibodies that can be used for development of an in vitro potency immunoassay ...

Adjunct Culture of Non-Starter Lactic Acid Bacteria for the Production of Provola Dei Nebrodi PDO Cheese: In Vitro Screening and Pilot-Scale Cheese-Making

(GTG)5-primer, and by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI- TOF MS). Twenty-seven strains, included in the qualified presumption of safety (QPS) list, were tested for ...

Chemical and toxciological characterization of e-liquid cigarettes

information on their genotoxicity was present. For four of these flavourings, a commercial standard was available and thus could be tested in vitro using an Ames- and micronucleus test. One of the four ...

Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo

influence of NP agglomeration on their toxicity/biological responses in vitro and in vivo. Results: We tested two TiO2 NP s with different primary sizes (17 and 117 nm) and prepared ad-hoc suspensions ...

Report on a New Opioid NPS: Chemical and In Vitro Functional Characterization of a Structural Isomer of the MT-45 Derivative DiphenpipenolAbstract

Publication Type: Peer reviewed scientific article Authors: Annelies Cannaert; Fabian Hulpia; Martijn Risseeuw; Katleen Van Uytfanghe; Eric Deconinck; Van Calenbergh, Serge; Peter Blanckaert; Stove, Christophe Source: Journal of Analytical Toxicology (202 ...

Risk assessment of ochratoxin A in food

tumours in rodents. OTA is genotoxic both in vitro and in vivo; however, the mechanisms of genotoxicity are unclear. Direct and indirect genotoxic and non‐genotoxic modes of action might each contribute to ...

Phytochemical screening, antioxidant, anticoagulant and in vitro toxic and genotoxic properties of aerial parts extracts of Fumaria officinalis L. growing in Tunisia

Number 273 (2020) Keywords: Comet Assay Extracts Flavonoid content Fumaria officinalis L. genotoxicity In vitro toxicity Phenolic content Vitotox test Abstract: Fumaria is an important plant species with ...

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