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interactomics

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Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans

interactomic polymerase Abstract: The optimized exploitation of cell resources is one cornerstone of a successful infection. Differential mapping of host-pathogen protein-protein interactions (PPI s) on the ...

Systematic identification of hypothetical bacteriophage proteins targeting key protein complexes of pseudomonas aeruginosa

assays, we further mapped the inhibitory interaction of gp12 of phage 14-1 to the alpha subunit of the RNA polymerase. Together, our data demonstrate the powerful use of interactomics to unravel the ...

Attributes of short linear motifs.

mediated by large, structured domains. However, it has become clear that the interactome comprises a wide range of binding interfaces with varying degrees of flexibility, ranging from rigid globular domains ...

Viral interference of the bacterial RNA metabolism machinery.

a unique interaction between a protein encoded by the giant myovirus phiKZ and the Pseudomonas aeruginosa RNA degradosome. Crystallography, site-directed mutagenesis and interactomics approaches revealed ...

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