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RNA-based drug susceptibility testing of Mycobacterium tuberculosis

the knowledge on resistance mutations which is limited for especially 2nd-line and new drugs, (b) do not distinguish living from death cells, (c) ignore all intrinsic resistance mechanisms like efflux ...

Genetic Basis and Clonal Population Structure of Antibiotic Resistance in Isolated From Broiler Carcasses in Belgium.

in this study provide better understanding of the phenotypic and the molecular basis of antibiotic resistance in, unraveling some the mechanisms which confer antimicrobial resistance and particular ...

The Phage-Encoded-Acetyltransferase Rac Mediates Inactivation of Transcription by Cleavage of the RNA Polymerase Alpha Subunit.

disconnects the C-terminal domain, required for transcription initiation from most highly active cellular promoters. To achieve this, Rac likely taps into a novel post-translational modification (PTM) mechanism ...

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