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MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles
potential to provide a cost-effective and fast alternative for classical phenotypic DST, independent of the mechanism of drug resistance. However, a current lack of automation hinders implementation in ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
However, transcriptional analyses can be a powerful tool as well. Analyses on susceptible strains provide information on the response to the stress a drug is causing, showing which mechanisms are activated ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
a powerful tool as well. Analyses on susceptible strains provide information on the response to the stress a drug is causing, showing which mechanisms are activated to counter the effect of the drug. This ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
resistance mutations, (b) do not distinguish living from dead cells, (c) ignore all intrinsic resistance mechanisms, and (d) ignore the influence of compensatory mutations. Objectives We introduce ...