Search results - 371 results

Batch release of vaccines in Europe: from method transfer to first commercial batch available on the market. Straightforward approach that requires a proactive mindset of the manufacturer.

responsibility to choose an OMCL belonging to the OMCL network. This choice, which is free, should be made before filing of the MA application. The initial process involves the transfer of the analytical methods ...

Biodiversity and human health: mechanisms and evidence of the positive health effects of diversity in nature and green spaces.

developed methods are needed to quantify short- and long-term health effects of exposure to perceived and objectively measured species diversity, including health effects of nature-based solutions and ...

Comparison of Droplet Digital PCR and qPCR for the Quantification of Shiga Toxin-Producing Escherichia coli in Bovine Feces.

PCR (qPCR), which has its specific limitations. Droplet digital PCR (ddPCR) has been proposed as a method to overcome many of the drawbacks of qPCR. This end-point amplification PCR is capable of ...

Detection of false negative Pap smears by rapid reviewing. A metaanalysis.

Laboratories Mass Screening Papanicolaou Test Quality Control Uterine Cervical Neoplasms Vaginal Smears Abstract: OBJECTIVE: To explore the diagnostic validity of rapid reviewing (RR) as a quality control method ...

Dietary silver nanoparticles can disturb the gut microbiota in mice.

microbiota in mice at doses relevant for currently estimated human intake. METHODS: Mice were orally exposed to food (pellets) supplemented with increasing doses of Ag NP (0, 46, 460 or 4600 ppb) during 28 d. ...

Genome mapping of Clostridium perfringens strains with I-CeuI shows many virulence genes to be plasmid-borne53

Endodeoxyribonucleases Endotoxins enterotoxin Enterotoxins food France gene Genes Genes,Bacterial genetics Genome im IS journal mapping method methods ON Operon paris pathogenicity Plasmids poisoning ...

Immediate referral to colposcopy versus cytological surveillance for minor cervical cytological abnormalities in the absence of HPV test.

cells of undetermined significance —  ASCUS or low-grade squamous intra-epithelial lesions —  LSIL) at primary screening in the absence of HPV (human papillomavirus) DNA  test. SEARCH METHODS: We searched ...

The impact of individual-level heterogeneity on estimated infectious disease burden: a simulation study.

to investigate to what extent ignoring the presence of heterogeneity could bias DALY  computation. METHODS: Simulations using individual-based models for hypothetical infectious diseases with short and ...

The impact of regular school closure on seasonal influenza epidemics: a data-driven spatial transmission model for Belgium.

community. The policy is still however highly debated because of controversial evidence. Moreover, the specific mechanisms leading to mitigation are not clearly identified. METHODS: We introduced a stochastic ...

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