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RNA-based drug susceptibility testing of Mycobacterium tuberculosis

phenotypic Drug Susceptibility Testing (DST) of M. tuberculosis (Mtb), multiple DNA-based methods were successfully introduced over the last years. Although these are fast and sensitive, they (a) are based on ...

Molecular epidemiology and antimicrobial resistance mechanisms of Campylobacter coli from diarrhoeal patients and broiler carcasses in Belgium.

Emerg Dis (2018) Keywords: Antimicrobial resistance Campylobacter Abstract: The aim of this study was to better understand the molecular epidemiology of Campylobacter coli isolated from multiple sources ...

Eight years after an international workshop on myotonic dystrophy patient registries: case study of a global collaboration for a rare disease.

an estimated 10 per 100,000 people. It is a multisystemic disorder affecting multiple generations with increasing severity. There are currently no licenced therapies to reverse, slow down or cure its ...

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

protease that mediates the activation of several innate and adaptive immune cells in response to multiple receptors, and therapeutic MALT1 targeting is believed to be a valid approach for autoimmunity and ...

Multivalent binding of herpesvirus to living cells is tightly regulated during infection.

the cell surface. While multiple parallel interactions would allow strong virus attachment, a low number of bonds could be preferred to allow lateral diffusion toward specific receptors and to promote ...

Y-box-binding protein 1 supports the early and late steps of HIV replication.

conclusion, our results indicate that YB-1 affects multiple stages of HIV replication. Future research on the interaction between YB-1 and the virus will reveal whether this protein qualifies as a new ...

Roadbook for the implementation of next-generation sequencing in clinical practice in oncology and hemato-oncology in Belgium.

diagnostics in cancer patients, analysis by next-generation sequencing is becoming part of routine clinical practice. The introduction of this complex technology in a healthcare system comes with multiple ...

Comparative genomics of quinolone-resistant and susceptible Campylobacter jejuni of poultry origin from major poultry producing European countries (GENCAMP)

fluoroquinolone resistance and ST-types. The cgMLST trees of only FQ-R and FQ-S isolates showed that isolates from the same country of origin were distributed into multiple clusters similarly to the trees combining ...

Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study.

assays in tuberculosis (TB) laboratory diagnosis requires effective management of time and resources. OBJECTIVE: To further develop and assess at multiple centres a time-and-motion (T&M) tool as an ...

Seroprevalence and risk factors related to small ruminant lentivirus infections in Belgian sheep and goats.

was 6% (CI  : 3-12) and the between-herd seroprevalence was 13% (CI  : 7-23). Multiple sheep and goat breeds were found SRLV seropositive. Answers provided during the questionnaire confirmed the mostly ...

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