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Clinical performance of the novel full-genotyping OncoPredict HPV Quantitative Typing assay using the VALGENT framework.

multiplex real-time PCR quantitative assay targeting E6 / E7 genes, allowing individual viral load determination of 12 high-risk (HR) HPV types. Quality controls for sample adequacy, efficiency of nucleic ...

Risk Factors Associated with Severe RSV Infection in Infants: What Is the Role of Viral Co-Infections?

for a panel of 16 different respiratory viruses with multiplex RT-qPCR. Disease severity was assessed with traditional clinical parameters and scoring systems. A total of 120 patients were included, of ...

Evaluation of the clinical performance of OncoPredict HPV® SCR assay within the VALGENT‐2 framework

papillomavirus (HPV) assays used in cervical cancer screening should be clinically validated according to international criteria. OncoPredict HPV ® Screening (SCR) is a partial genotyping multiplex real-time PCR ...

Development and validation of a microfluidic multiplex immunoassay for the determination of levels and avidity of serum antibodies to tetanus, diphtheria and pertussis antigens.

Methods, Volume 503 (2022) Keywords: Antibodies, Bacterial Bordetella pertussis Diphtheria Humans Immunoassay Immunoglobulin G Microfluidics Pertussis Toxin Tetanus Whooping Cough Abstract: A multiplex assay ...

Evaluating SARS-CoV-2 spike and nucleocapsid proteins as targets for antibody detection in severe and mild COVID-19 cases using a Luminex bead-based assay.

(e.g. virus neutralization assays), or are expensive with suboptimal specificity (e.g. commercial ELISA s and RDT s). Bead-based assays offer a cost-effective alternative and allow for multiplexing to ...

Seroprevalence of Antibodies against Diphtheria, Tetanus and Pertussis in Adult At-Risk Patients.

of antibodies against diphtheria, tetanus and pertussis to evaluate whether current vaccination programs in Belgium are adequate. Antibody titers were assessed with a bead-based multiplex assay in ...

A new multiplex RT-qPCR method for the simultaneous detection and discrimination of Zika and chikungunya viruses

Dominique Rousset; Steven Van Gucht; Nancy Roosens Source: International Journal of Infectious Diseases, Volume 92 (2020) Keywords: Chikungunya virus discrimination identification multiplex RT-qPCR Zika virus ...

A new multiplex RT-qPCR method for the simultaneous detection and discrimination of Zika and chikungunya viruses.

worldwide a wave of concern. To treat patients in an early stage and prevent diffusion of the outbreak, an early diagnosis, and thus fast and adequate detection, is needed. To this aim, a multiplex reverse ...

Perspectives on the integration of Immuno-Oncology Biomarkers and drugs in a Health Care setting.

validity and utility requirements of predictive immuno-oncology biomarkers is highlighted and an overview is given on the evolution towards multiplex or omics-based assays together with its challenges and ...

Optimization and Application of a Multiplex Digital PCR Assay for the Detection of SARS-CoV-2 Variants of Concern in Belgian Influent Wastewater.

Koenraad Van Hoorde; Alexander L N van Nuijs; Peter Delputte Source: Viruses, Volume 14, Issue 3 (2022) Keywords: Belgium COVID-19 Humans Multiplex Polymerase Chain Reaction Pandemics RNA, Viral SARS-CoV-2 ...

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