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In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment

effects of long-term exposure to ELF-(E) MF s on the genetic material and the impact of long-term pre-exposure to ELF-(E) MF s on the sensitivity of cells to the damage induced by known mutagens are needed. ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...

Performance of in silico models for mutagenicity prediction of food contact materials

Toxicological Sciences, Volume 163, Issue 2 (2018) Keywords: (Q)SAR food contact materials In silico mutagenicity VALIDATION Abstract: In silico methodologies, such as (quantitative) structure-activity ...

Coatings in food contact materials: Potential source of genotoxic contaminants?

Food Chem Toxicol, Volume 106, Issue Pt A, Number 505, p.496-505 (2017) Keywords: Consumer Product Safety Food Contamination Food Packaging Humans Mutagenicity Tests Mutagens Abstract: Up till now, no ...

(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.

Sabine; Benfenati, Emilio; Mertens, Birgit; Rogiers, Vera Source: Food Chem Toxicol, Volume 102, Number 119, p.109-119 (2017) Keywords: Computer Simulation Food Packaging Mutagenicity Tests Organic ...

Isolation and characterization of the compounds responsible for the antimutagenic activity of Combretum microphyllum (Combretaceae) leaf extracts

inhibit the pathological process resulting from exposure to mutagens. Investigation of the antimutagenic potential of traditional medicinal plants and compounds isolated from plant extracts provides one of ...

Slurry photocatalytic membrane reactor technology for removal of pharmaceutical compounds from wastewater: Towards cytostatic drug elimination

compounds and their metabolites, as well as their degraded by-products have genotoxic and mutagenic effects. A major challenge of cytostatic removal stands in the fact that most drugs are delivered to ...

The correlation between antimutagenic activity and total phenolic content of extracts of 31 plant species with high antioxidant activity.

Altern Med, Volume 16, Issue 1, Number 13, p.490 (2016) Keywords: Antimutagenic Agents Antioxidants Mutagenicity Tests Phenols Plant Extracts Plant Leaves Plants Salmonella typhimurium Abstract: ...

In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.

Alessandra; Milushev, Dimiter; Benfenati, Emilio; Rogiers, Vera; Doktorova, Tatyana Y Source: Mutagenesis, Volume 31, Number 461, p.453-61 (2016) Keywords: Cosmetics In silico Mutagenicity Tests Transcriptomics ...

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