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Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

Instillation of NN-etched at the highest dose induced influx of neutrophils into the lungs at all time points and increased Saa3 mRNA levels in lung tissue on day 1 and 3 after exposure. No genotoxicity was ...

Allergic Asthma Favors Growth in the Lungs of Infected Mice.

dense aggregates of infected cells composed mainly of alveolar macrophages (CD11 c F4 /80 MHCII) surrounded by neutrophils (Ly-6G). Asthma-induced susceptibility appears to be dependent on CD4 T cells, ...

STAT6 Mediates Footpad Immunopathology in the Absence of IL-12p40 Following Infection of Susceptible BALB/c Mice With.

coincides with the presence of neutrophils displaying an altered phenotype characterized by a lower expression of surface markers Ly6C, CD11 b, and Ly6G. These neutrophils exhibited very lower levels of ...

Encephalomyocarditis virus in a captive Malayan tapir ().

negative, except for encephalomyocarditis virus. Histopathology revealed mineralisation of myocardial cells and interstitial infiltration of lymphocytes, plasma cells and less neutrophils ...

Mice genetically inactivated in interleukin-17A receptor are defective in long-term control of Mycobacterium tuberculosis infection.

Tuberculosis Abstract: Interleukin-17A (IL-17A), a pro-inflammatory cytokine acting on neutrophil recruitment, is known to play an important role during Mycobacterium tuberculosis infection, but the role of ...

Mucosal and systemic immune responses to Mycobacterium tuberculosis antigen 85A following its co-delivery with CpG, MPLA or LTB to the lungs in mice1377

a production of IL-5 but not IFN-? by spleen mononuclear cells in vitro. CpG did not induce inflammation in the lungs while LTB and MPLA showed a transient inflammation including a neutrophil influx one day ...

The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer

CXCL8 chemoattract pro-tumoral neutrophils. In addition, angiogenic CXCR2 ligands stimulate the formation of new blood vessels, facilitating tumor progression. The CXCR4 ligand SDF-1/ CXCL12 also promotes ...

Isotypic neutralizing antibodies against mouse GCP-2/CXCL6 inhibit melanoma growth and metastasis

as angiogenesis inducer and neutrophil chemoattractant. The neutralizing capacity and specificity of monoclonal mouse anti-murine (mu) GCP-2/ CXCL6 antibodies were evidenced by granulocyte chemotaxis ...

Interleukin-17 regulates chemokine and gelatinase B expression in fibroblasts to recruit both neutrophils and monocytes

monocytes and neutrophils to the inflammatory focus Service:  Qualité des laboratoires Kwaliteit van laboratoria Quality of laboratories Manuscript versions:  DOI:  ...

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