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Defining optimal triage strategies for hrHPV screen positive women- an evaluation of HPV 16/18 genotyping, cytology and p16/Ki-67 cyto-immunochemistry.
HPV16/18 negative women had a post test probability of CIN2+ of 1.7% and 0.6% if also LBC negative. IMPACT: This is one of the few studies to directly compare the performance of triage strategies of hrHPV+ ...
Pregnancy outcome after cervical conisation: A 2nd retrospective cohort study in the Leuven University Hospital.
with a lower risk of obstetrical harms on a subsequent pregnancy. STUDY DESIGN: A retrospective matched cohort study was performed in a tertiary referral unit in Belgium. A total of 97 women were ...
Ethnicity impacts the cystic fibrosis diagnosis: A note of caution.
parameters in all patients, yet the influence of ethnicity has only scarcely been studied. We aimed at elucidating the impact of Asian descent on the diagnosis of CF. METHODS: We performed a retrospective ...
Impact of anaesthesia mode on evaluation of LEEP specimen dimensions.
fluid displacement. RESULTS: One hundred patients were included and 35% of LEEP were performed under local anaesthesia. There was a significant difference in height of specimens depending on anaesthesia mode: after ...
Diagnostic accuracy of p16(INK4a) immunohistochemistry in oropharyngeal squamous cell carcinomas: A systematic review and meta-analysis.
meta-analysis to determine the diagnostic accuracy of p16(INK4 a) immunohistochemistry (IHC) to identify HPV-induced OPSCC. We identified all studies that performed p16(INK4 a) IHC (index test) and HPV E6 / E7 ...
Immediate referral to colposcopy versus cytological surveillance for low-grade cervical cytological abnormalities in the absence of HPV test: A systematic review and a meta-analysis of the literature.
performed a systematic review and meta-analysis to explore the optimum management strategy for women with atypical squamous cells of undetermined significance (ASCUS /borderline) or low-grade squamous ...
Performance of a Cartridge-Based Assay for Detection of Clinically Significant Human Papillomavirus (HPV) Infection: Lessons from VALGENT (Validation of HPV Genotyping Tests).
performance. Through VALGENT, we assessed the performance of the cartridge-based Xpert HPV assay (Xpert HPV), which detects 14 high-risk (HR) types and resolves HPV16 and HPV18 /45. Samples from women attending ...
Clinical action measures improve the reliability of feedback on quality of care in diabetes centres: a retrospective cohort study.
a change in position among centres (‘poor’, ‘good’ or ‘excellent’ performer) for 5-10 % of the centres. CONCLUSIONS: Judging quality of diabetes care of a centre based on a TM may be misleading. ...
Clinical and analytical performance of the PapilloCheck HPV-Screening assay using the VALGENT framework.
Publication Type: Peer reviewed scientific article Authors: Heard, I; Cuschieri, K; Geraets, D T; Quint, W; M. Arbyn Source: J Clin Virol, Volume 81, p.6-11 (2016) Abstract: BACKGROUND: The benefit of HPV testing for cervical cancer screening and disease ...
Adverse obstetric outcomes after local treatment for cervical preinvasive and early invasive disease according to cone depth: systematic review and meta-analysis.
data and performed quality assessment using the Newcastle-Ottawa criteria. Studies were classified according to method and obstetric endpoint. Pooled risk ratios were calculated with a random effect ...