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Comparative dissolution study on substandard and falsified antibiotics encountered in Belgium

parameters of drug quality control [2]. In this context, SF antimicrobials containing the correct dosage of claimed API s can exhibit poor dissolution performance. Thus, it is necessary and crucial to execute ...

Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market.

a screening and a quantification method using ultra-high performance liquid chromatography with tandem mass spectrometry (UHPLC- MS) and diode array detection (UHPLC- DAD), respectively were developed and ...

Impurity profiling of the most frequently encountered falsified polypeptide drugs on the Belgian market

biotherapeutics were already analysed, looking at a specific aspect of their quality or identity, no systematic studies have been performed regarding the presence of different impurities or possible contaminations. ...

Analysis of illegal peptide drugs via HILIC-DAD-MS.

five different HILIC columns were selected and screened for their chromatographic performance. Among those columns, the ZIC HILIC column showed the best performance under the tested screening conditions ...

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