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Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

(WGS) data. Performance was insufficient to support the use of WGS as an alternative to conventional phenotype-based DST, due to mutation catalogue limitations.  Here we present a new tool,, which ...

Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study.

1060 specimens were tested using four laboratory assays. The number of specimens per batch varied from one to 60; a total of 64 recordings were performed. Theoretical hands-on times per specimen (TTPS) ...

Molecular epidemiology of Mycobacterium tuberculosis complex in Brussels, 2010-2013.

become an important determinant for TB control programs. However, sufficient financial means need to be available to perform all required epidemiological investigations. Health Topics:  Tuberculosis ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

is incubated in absence of the drug. Multiplex mRNA quantification is performed directly on crude cell lysates using a combination of the bead-based MagPixTM (Luminex) and QuantigeneTM Plex (Thermo ...

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