Search results - 7 results
Non-surgical periodontal therapy with systemic antibiotics in patients with untreated aggressive periodontitis: a systematic review and meta-analysis.
for additional information. The following outcome measures were analysed: mean probing pocket depth reduction, mean clinical attachment level gain and mean bleeding on probing change. Extracted data ...
Activity limitations predict health care expenditures in the general population in Belgium.
limitations). The association between activity limitation and health care expenditures is stronger for reimbursed health care costs than for out-of-pocket payments. CONCLUSION: In the absence of chronic ...
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
nucleotide-binding pocket, and hence have a more narrow spectrum of activity and are more prone to resistance development. Here, we report a novel NNI, GPC- N114 ...
HIV-1 IN/Pol recruits LEDGF/p75 into viral particles.
preintegration complex to the chromatin through a direct interaction with integrase (IN). Small molecules that bind the LEDGF /p75 binding pocket of the HIV IN dimer (LEDGIN s) block HIV replication through ...
The use of serosurveys following emergency vaccination, to recover the status of "foot-and-mouth disease free where vaccination is not practised".
different seropositive findings. This derives largely from uncertainty over the extent of localised pockets of virus infection that may remain within vaccinated populations and the circumstances that permit ...
Universal hepatitis B vaccination in Belgium: impact on serological markers 3 and 7 years after implementation.
which may give rise to pockets of susceptible young adults in the future. Service: Maladies virales Virale ziekten Viral diseases Manuscript versions: DOI: http://dx.doi.org/10.1017/S0950268813001064 ...
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
more mobility to F224 and, hence, reducing the affinity for BPIP and VP32947. It is concluded that a single drug-binding pocket exists within the finger domain region of the BVDV RdRp that consists of ...