Search results - 167 results

A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells

Publication Type: Scientific poster, presentation or proceeding Authors: Julie Buick; Eunnara Cho; Anouck Thienpont; Birgit Mertens; Andrew Williams; Carole Yauk; Matthew Meier Source: Health Canada ...

Development of novel analytical methods to trace small micro- and nanoplastics in food matrices

Publication Type: Scientific poster, presentation or proceeding Authors: M. Fadda; A. Sacco; K. Altmann; R. Drexel; F. Meier; Charlotte Wouters; A. M. Rossi; A. M. Giovannozzi Source: 7th IMEKO ...

The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)

Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Carole Yauk; Stefaan Verhulst; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...

An AOP-based IATA to pave the way toward animal-free genotoxicity testing

Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: adverse outcome pathways genotoxicity ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; ...

Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals

Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; ...

Oncolytic Viruses: An Inventory of Shedding Data from Clinical Trials and Elements for the Environmental Risk Assessment.

replication-defective viral vectors commonly used in gene therapy or vaccination. To our knowledge, this article presents the most extensive and up-to-date review of shedding data reported with OV employed in clinics. ...

Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment

Publication Type: Scientific poster, presentation or proceeding Authors: Alexandra Schaffert; Sivakumar Murugadoss; Birgit Mertens; Tom Roos; Ronette Gehring; Nunzia Linzalone; Gabriele Donzelli; ...

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