Search results - 167 results
A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells
Publication Type: Scientific poster, presentation or proceeding Authors: Julie Buick; Eunnara Cho; Anouck Thienpont; Birgit Mertens; Andrew Williams; Carole Yauk; Matthew Meier Source: Health Canada ...
Development of novel analytical methods to trace small micro- and nanoplastics in food matrices
Publication Type: Scientific poster, presentation or proceeding Authors: M. Fadda; A. Sacco; K. Altmann; R. Drexel; F. Meier; Charlotte Wouters; A. M. Rossi; A. M. Giovannozzi Source: 7th IMEKO ...
EFSA Project on the use of New Approach Methodologies (NAMs) for the hazard assessment of nanofibres. Lot 1, nanocellulose oral exposure: gastrointestinal digestion, nanofibres uptake and local effects
NC. In the present project, a NAM-based IATA for addressing data gaps in the assessment of potential hazards associated to NC oral exposure was considered. This IATA focused on three main pillars, i.e. ...
The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Carole Yauk; Stefaan Verhulst; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...
An AOP-based IATA to pave the way toward animal-free genotoxicity testing
Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: adverse outcome pathways genotoxicity ...
Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake
Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; ...
Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...
Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake
Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; ...
Oncolytic Viruses: An Inventory of Shedding Data from Clinical Trials and Elements for the Environmental Risk Assessment.
replication-defective viral vectors commonly used in gene therapy or vaccination. To our knowledge, this article presents the most extensive and up-to-date review of shedding data reported with OV employed in clinics. ...
Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment
Publication Type: Scientific poster, presentation or proceeding Authors: Alexandra Schaffert; Sivakumar Murugadoss; Birgit Mertens; Tom Roos; Ronette Gehring; Nunzia Linzalone; Gabriele Donzelli; ...