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Study of the underlying mechanisms and consequences of pathogenicity differences between two in vitro selected G1-H9N2 clones originating from a single isolate.

H9N2 clones, selected on different cell types, named MDCK-and CEF-clone in regards to the cell culture used, were studied in vivo, revealing two different virulence phenotypes. Subsequently, the ...

Global burden of intellectual disability resulting from dietary exposure to lead, 2015

an uncertainty range of 0-31 million DALY s. Significant uncertainties regarding exposure and dose-response relationships, however, warrant continued investigation. Health Topics:  Burden of disease ...

Prevention of Cervical Cancer: Guideline of the DGGG and the DKG (S3 Level, AWMF Register Number 015/027OL, December 2017)- Part 2 on Triage, Treatment and Follow-up.

important need, outlined in the National Cancer Plan, with regard to screening for cervical cancer, as this guideline aims to provide important information and support for planned organized screening for ...

Risk to human health related to the presence of perfluorooctane sulfonic acid and perfluorooctanoic acid in food

and perfluorooctanoic acid (PFOA) in food. Regarding PFOS and PFOA occurrence, the final data set available for dietary exposure assessment contained a total of 20,019 analytical results (PFOS ...

Falsification of biotechnology drugs: current dangers and/or future disasters?

falsified. The danger regarding the use of these falsified polypeptide drugs lies in the fact that end-users have no guarantee of the safety and efficacy of these preparations. Multiple reports have namely ...

Generating the evidence for risk reduction: a contribution to the future of food-based dietary guidelines.

diseases. As a consequence, food-based dietary guidelines (FBDG) are now the preferred approach to guide the population regarding their dietary habits. However, such guidelines should be based on a high grade ...

Validation of intra- and inter-laboratory reproducibility of the Xpert HPV assay according to the international guidelines for cervical cancer screening.

intra- and inter-laboratory agreement regarding detection of high-risk HPV DNA exceeding 87% with kappa ≥0.5. RESULTS The Xpert HPV assay showed high intra-laboratory reproducibility with an overall ...

Differences in primary palliative care between people with organ failure and people with cancer: An international mortality follow-back study using quality indicators.

registration form was used to construct quality indicators regarding regular pain measurement, acceptance of the approaching end of life, communication about disease-related topics with patient and next-of-kin; ...

Very Long Persistence of Botulinum Toxin B in a Patient’s Serum

of BoNT B in the serum and ii) the risks related to the preparation of artisanal products as well as the importance of an efficient communication to citizens regarding preservation methods of ...

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