Search results - 546 results
The use of Stationary Phase Optimized Selectivity Liquid Chromatography for the development of herbal fingerprints to detect targeted plants in plant food supplements.
control is performed and that they could contain herbs or plants that are regulated. Stationary Phase Optimized Selectivity Liquid Chromatography (SOS- LC) was evaluated for the development of specific ...
Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4-5 December 2014).
for drug developers and regulators were presented. These methods are described in the present report: they include five advanced methods for data analysis (empirical regression models, pharmacometrics ...
Commentary on the MID3 Good Practices Paper.
regulators agreed to the necessity to build expertise to be able to review M&S data provided by companies in their dossier. This led to the establishment of the EMA Modelling and Simulation Working Group ...
Vaccinatiebeleid en advies in België
and regulations, monographs and opinions FOS Classification: 3 MEDICAL AND HEALTH SCIENCES 3.03 Health sciences ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
transcriptional response was mapped, revealing lists of up- and down-regulated genes. As an example and in accordance with previous studies, the highest induced genes in the presence of isoniazid belong to ...
PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes.
response of astrocytes to glutamate remains largely unknown. Considering that kinases are frequently involved in the regulation of G protein-coupled receptors, we have examined a putative link between the ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
down-regulated genes. As an example and in accordance with previous studies, the highest induced genes in the presence of isoniazid belong to a cluster of genes that encodes components of the FAS- II (fatty acid ...
Assessment of dietary intake of 10 intense sweeteners by the Italian population.
analyzed in order to establish the concentration levels. Intense sweeteners were only found in foods belonging to 8 sugar-free food categories out of 37 regulated. The dietary exposure was estimated using ...
Chromatographic fingerprinting as a strategy to identify regulated plants in illegal herbal supplements.
Publication Type: Peer reviewed scientific article Authors: Custers, D; Van Praag, N; Patricia Courselle; Apers, S; Eric Deconinck Source: Talanta, Volume 164, p.490-502 (2017) Abstract: Erectile dysfunction (ED) is a sexual disorder characterized by the ...
The role of methylation, DNA polymorphisms and microRNAs on HLA-G expression in human embryonic stem cells.
investigated how HLA-G expression is linked to the patterns of promoter methylation and explored the role of the 3’ UTR polymorphic sites and their binding microRNAs on the post-transcriptional regulation of ...