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RE-PLACE: an ambitious project to collect animal-free methodologies in one central database

Publication Type: Scientific poster, presentation or proceeding Authors: V Rogiers; Mieke Van Mulders; N. Liodo Missigba; Birgit Mertens Source: BCLAS, Issue BCLAS, Blankenberge, Belgium (2019) Service:  Évaluation des risques et de l'impact sur la s ...

RE-Place: a database compiling New Approach Methodologies

Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens; Mieke Van Mulders; N. Liodo Missigba; V. Rogiers Source: Animals in research, no unless, Issue KU Leuven, Leuven, Belgium (2019) Service:  Évaluation des risques et d ...

Development of a real-time PCR method for the genoserotyping of Salmonella Paratyphi B variant Java.

reaching an accuracy, compared with the classical methods, of 98% for serotyping by slide agglutination and 100% for replacement of the biochemical test. The developed real-time PCR permits to save time and ...

Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.

testing, such strategies should respect the 3R principles (Replacement, Reduction, Refinement). In the present study, a strategy based on non-animal approaches was developed to prioritize non-evaluated ...

Black aspergilli: A remaining challenge in fungal taxonomy?

up to clade level in the clinical lab. Our results indicate that MALDI- TOF MS can be a powerful tool to replace classical morphology. Health Topics:  Culture collection Cultuurcollectie Collection de ...

Seasonal Genetic Drift of Human Influenza A Virus Quasispecies Revealed by Deep Sequencing

Werf Source: Frontiers in Microbiology, Volume 9 (2018) Abstract: After a pandemic wave in 2009 following their introduction in the human population, the H1N1 pdm09 viruses replaced the previously ...

RE-Place: centralizing information on alternative methods to animal testing to promote knowledge sharing

Database in chemico In silico in vitro new approach methodologies replacement Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des risques et de ...

zDALY: An adjusted indicator to estimate the burden of zoonotic diseases.

trade-off for human life years. This is the time required to earn the income needed to replace that financial loss. This can then be assigned a DALY equivalent, termed animal loss equivalents (ALE), and added ...

RE-Place: Creation of a database for alternative methods to animal testing in the Flemish and Brussels region

Keywords: 3R alternative methods Database in chemico In silico in vitro new approach methodologies replacement Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  ...

Studiedag rond alternatieve methoden voor dierproeven in Vlaanderen. Het Kick-off symposium van RE-Place

alternative methods Database in chemico In silico in vitro new approach methodologies replacement Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des ...

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