Search results - 64 results
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
onset of intracellular viral RNA synthesis. Drug-resistant mutants carry the E291G mutation in the viral RNA-dependent RNA polymerase (RdRp). AG110-resistant virus is cross-resistant to the cyclic urea ...
Lethality and molecular characterization of an HPAI H5N1 virus isolated from eagles smuggled from Thailand into Europe.
resistance factors. Using infection experiments, we show that pathogenicity in chickens depends on breed, inoculation route (oculonasal vs. intramuscular), and dose. Additionally, in Muscovy ducks, ...
TSE detected in a Belgian ARR-homozygous sheep via active surveillance.
Animals Breeding Female Genetic Predisposition to Disease Genotype Population Surveillance Scrapie Sheep Sheep Diseases Abstract: It is commonly accepted that scrapie-resistance and-susceptibility in sheep ...
Helicobacter equorum sp. nov., a urease-negative Helicobacter species isolated from horse faeces.
resistant to cephalotin and nalidixic acid and susceptible to metronidazole. Analysis of the 16S and 23S rRNA gene sequences of the two novel strains identified them as representing a single species within ...
Avian influenza: mini-review, European control measures and current situation in Asia.
westward. In addition, its virulence is extremely higher than other HPAI, like H7N7. Moreover, the avian host range is expanding, as species previously considered resistant, now get infected and can ...
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Johan Source: J Virol, Volume 80, Issue 1, p.149-60 (2006) Keywords: Antiviral Agents Diarrhea Virus 1, Bovine Viral Drug Resistance, Viral Imidazoles Lethal Dose 50 Mutation Pestivirus Pyridines RNA ...
Virulence-associated traits in avian Escherichia coli: comparison between isolates from colibacillosis-affected and clinically healthy layer flocks.
caecal and 20 extra-intestinal isolates. The examined characteristics were adhesins, invasivity in T84 cell culture, serum resistance, iron uptake, colicin production, and toxinogenicity. The following ...
Streptomycin as a selective agent to facilitate recovery and isolation of introduced and indigenous Sphingomonas from environmental samples.
showing that the capacity to resist high concentrations of Sm is a common characteristic within Sphingomonas. Incorporation of Sm into the mineral medium led to a significant reduction in the background ...
In vitro susceptibilities of Mycoplasma hyopneumoniae field isolates.
Issue 11, p.4470-2 (2004) Keywords: Animals Anti-Bacterial Agents Drug Resistance, Bacterial Microbial Sensitivity Tests Mycoplasma Pneumonia, Mycoplasma Swine Swine Diseases Abstract: The in vitro ...
Conditional expression of type I interferon-induced bovine Mx1 GTPase in a stable transgenic vero cell line interferes with replication of vesicular stomatitis virus.
Humans Interferon Type I Myxovirus Resistance Proteins Transgenes Vero Cells Vesicular stomatitis Indiana virus Vesiculovirus Virus Replication Abstract: In some vertebrate species, type ...