Search results - 10 results

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

has become a World Health Organization priority. We previously developed a software tool,, which provided offline species identification and drug resistance predictions for from whole genome sequencing ...

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.

fleeing hardship for refuge in Europe is heightened. We describe the cross-border European response to an outbreak of multidrug-resistant tuberculosis among patients from the Horn of Africa and Sudan. ...

Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.

Volume 22, Issue 1 (2018) Keywords: Carbapenems repurposed drugs XDR-TB Abstract: BACKGROUND: Extensively drug-resistant tuberculosis (XDR- TB), defined as TB caused by a Mycobacterium strain resistant to ...

Molecular epidemiology of Mycobacterium tuberculosis complex in Brussels, 2010-2013.

Resistance, Multiple, Bacterial Emigrants and Immigrants Family Health Female Genetic Variation Genotype Hospitals, Urban Humans incidence Male middle aged Mycobacterium tuberculosis Phylogeny Population ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Mycobacteria. 34 clinical M. tuberculosis isolates were investigated for their resistance profile to four different drugs (rifampicin, isoniazid, ethambutol and linezolid), yielding a 100% concordance to the ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

recent report of the WHO ranks tuberculosis (TB) alongside HIV as a leading cause of death by infectious diseases. In combination, the spread of (multi-)drug resistant Mycobacterium tuberculosis is rising ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

(TB) alongside HIV as a leading cause of death by infectious diseases. In combination, the spread of (multi-)drug resistant Mycobacterium tuberculosis is rising (480 000 new cases), impeding the ...

WIV-ISP's experiences in the use of MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Mycobacteria and their drug resistance profiles. By using an optimized extraction protocol, they successfully identified 88.14 % of 194 Mycobacterial strains at a species-level and 3.09 % at genus-level, using ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

Background Multidrug resistance of Tuberculosis strains (MDR- TB) are one of the major WHO health concerns. One of the challenges that hampers the effective response to MDR- TB is the long turnaround time of ...

Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid

incidence and counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains ...

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