Search results - 6 results

Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety

enrichment. All protocols that have been proposed have been chosen to be as close as possible to the ones currently used in the reference laboratories so they can be adapted to be used in routine in the future. ...

Development of a data-intensive centralized system for surveillance and outbreak investigation of bacterial pathogens using whole-genome sequencing

sequencing (WGS), the sequencing of (nearly) complete genomes, has had an enormous impact on almost all fields of biology. However, its successful integration into routine public health practice has lagged ...

Development of a genoserotyping system for the identification of Salmonella serotypes

accuracy, cost- and time-effectiveness of Salmonella serotype identification in a routine setting. The 4 MOL- PCR assays developed here are up to 7.5 less expensive than the classical methods and they are ...

Strategies to detect unauthorized GMO in the food and feed chain (PhD thesis)

pCAMBIA), were selected to develop a strategy allowing to detect and characterize a broad range of GMO. This strategy, fully integrated in the GMO routine analysis, consists to characterize sequences ...

Strategies to detect unauthorized genetically modified organisms in food and feed chain

routine analysis, consists to characterize sequences surrounding detected key transgenic elements using a DNA walking approach. By this way, the acquisition of sequences from the junction between the ...

Exploring the added value of Whole Genome Sequencing in routine and pandemic viral surveillance

applications have remained unexploited in the context of routine surveillance, which is the core business of national reference centres and public health institutes such as Sciensano. The virus surveillance aims ...

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