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Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

of the mammalian cell entry family, that were identical with Mah 104 strain. Despite the obvious limitations of the mouse model, a striking link of virulence and identity at the genome level of porcine ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

(480 000 new cases), impeding the treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. However, transcriptional analyses can be ...

WIV-ISP's experiences in the use of MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Mycobacteria and their drug resistance profiles. By using an optimized extraction protocol, they successfully identified 88.14 % of 194 Mycobacterial strains at a species-level and 3.09 % at genus-level, using ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

Fisher) technology. The normalized expression levels are combined to one numeric value which determines the drug susceptibility of the investigated strain. Results We successfully developed 8 primary sets ...

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