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Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.

Volume 22, Issue 1 (2018) Keywords: Carbapenems repurposed drugs XDR-TB Abstract: BACKGROUND: Extensively drug-resistant tuberculosis (XDR- TB), defined as TB caused by a Mycobacterium strain resistant to ...

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

isolates of genotype MST91 and comparison with two well-studied M. avium subsp. hominissuis reference strains i.e. Mah 104 and Mah TH135, identified in the two MST22 isolates nine specific virulence factors ...

Molecular epidemiology of Mycobacterium tuberculosis complex in Brussels, 2010-2013.

years after the realization of initial prospective population-based molecular epidemiology investigations in this Region, a similar study over the period 2010-2013 was conducted. TB strains isolated from ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

However, transcriptional analyses can be a powerful tool as well. Analyses on susceptible strains provide information on the response to the stress a drug is causing, showing which mechanisms are activated ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

a powerful tool as well. Analyses on susceptible strains provide information on the response to the stress a drug is causing, showing which mechanisms are activated to counter the effect of the drug. This ...

WIV-ISP's experiences in the use of MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Mycobacteria and their drug resistance profiles. By using an optimized extraction protocol, they successfully identified 88.14 % of 194 Mycobacterial strains at a species-level and 3.09 % at genus-level, using ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

Background Multidrug resistance of Tuberculosis strains (MDR- TB) are one of the major WHO health concerns. One of the challenges that hampers the effective response to MDR- TB is the long turnaround time of ...

Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid

counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains to ...

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