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Attenuation of RNA viruses by redirecting their evolution in sequence space.
significant losses in viral fitness. In vivo, the viruses were attenuated, generated high levels of neutralizing antibodies and protected against lethal challenge. Our study demonstrates that cornering viruses ...
Influenza A virus co-opts ERI1 exonuclease bound to histone mRNA to promote viral transcription.
that are responsible for seasonal epidemics, but the interplay between viral proteins and cellular exonucleases has never been specifically studied. Here, using a stringent interactomics screening ...