Analytical evaluation of twenty assays for determination of thyrotropin (TSH)146

Last updated on 22-8-2019 by Anonymous (non vérifié)

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Peer reviewed scientific article

SCIENSANO

Résumé:

This paper summarises the results of the evaluation of several assays of thyrotropin in serum. The authors assessed 8 radioimmunoassays (IRMA techniques) and 10 enzyme immunoassays, including ELISA, luminescent immunometry and fluoroimmunometry, also covering a broad spectrum of actual assays. An unique protocol based on identical human samples for all assays was used in order to compare precision, linearity, detection limit, matrix effects and correlation. The authors found a wide spread in precision results between the evaluated assays; as distinct from enzyme immunoassays, discrepant ana…

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