Combination of analytical quality specifications based on biological within- and between-subject variation124

Last updated on 22-8-2019 by Anonymous (non vérifié)

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Peer reviewed scientific article



At a conference on ‘Strategies to Set Global Analytical Quality Specifications in Laboratory Medicine’ in Stockholm 1999, a hierarchy of models to set analytical quality specifications was decided. The consensus agreement from the conference defined the highest level as ‘evaluation of the effect of analytical performance on clinical outcomes in specific clinical settings’ and the second level as ‘data based on components of biological variation’. Here, the many proposals for analytical quality specifications based on biological variation are examined and the outcomes of the different models…

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