Last updated on 24-1-2025 by Stéphanie Depickère
Public Access
Peer reviewed scientific article
Anglais
SCIENSANO
Auteurs
Gemander, Nicolas; Delphine Kemlin; Stéphanie Depickère; Kelkar, Natasha S; Sharma, Shilpee; Pannus, Pieter; Alexandra Waegemans; Olislagers, Véronique; Daphnée Georges; Emilie Dhondt; Braga, Margarida; Heyndrickx, Leo; Michiels, Johan; Anaïs Thiriard; Anne Lemy; Baudoux, Thomas; Vandevenne, Marylène; Maria Goossens; André Matagne; I Desombere; Ariën, Kevin K; Margaret E Ackerman; Le Moine, Alain; Arnaud MarchantMots-clés
Résumé:
BACKGROUND: Clinical risk factors of deficient immune responses to COVID-19 mRNA vaccination in SARS-CoV-2 naive hemodialysis recipients (HDR) have already been identified. Clinical factors influencing hybrid immunity induced by SARS-CoV-2 infection and vaccination in HDR have not been reported.
METHODS: A comprehensive analysis of antibody (Ab) and T cell responses to two doses of BNT162b2 mRNA vaccination was performed in 103 HDR, including 75 SARS-CoV-2 naive and 28 experienced patients, and in 106 healthy controls (HC) not undergoing HD, including 40 SARS-CoV-2 naive and 66 experienc…