Development of a multiplex immunoassay for simultaneous detection of antigens in DTaP vaccines

Last updated on 16-1-2024 by Maxime Vermeulen

Scientific poster, presentation or proceeding




Routine batch quality testing before vaccine release, notably for potency evaluation, still relies on animal use for several animal and human vaccines. In this context, the VAC2VAC project is a public-private consortium of 22 partners funded by EU. Its main objective is to reduce the number of animal used for batch testing by developing immunoassays that could be implemented for routine potency assessment of vaccines. Our work focused on the development of a Luminex-based multiplex assay (four to six-plex assay depending on the number of pertussis antigens present in the formulation) to mon…

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